About
Proteins interact with each other and organize themselves into macromolecular machines (i.e., complexes) to carry out essential functions of cells.
Protein pairwise interactions and complexes
- We measured stable protein-protein interactions based co-fractionation mass spectrometry of 12 taxonomically diverse plant species (and tested in a 13th species, maize)
- Interactions can be queried using either UniProt Entry, Entry name, gene name, or TAIR AT locus ID.
- Higher-order multiprotein complexes were derived by clustering the pairwise interactions, and are presented with four different levels of clustering stringency, from most restrictive (smallest clusters) to most inclusive (largest clusters)
A note on orthology:
- As protein complexes were derived from multi-species data, they are indexed by eggNOG DB plant-level (virNOG) orthogroupID
- These orthogroups take the form ENOG411XXXX, and can be searched at the eggNOG website
- Due to gene expansions since the last common ancestor of plant, each orthogroup may contain more than one protein from a species
For further details see the publication describing this work:
Website contributers
  Claire McWhite(website)
  Kevin Drew (website)
  Edward Marcotte (website)
Contact
  cmcwhite (at) princeton.edu  marcotte (at) icmb.utexas.edu